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1

Clinical Pharmacokinetics and Pharmacodynamics of Solifenacin

Oxana Doroshyenko, Prof. Dr. med. Uwe Fuhr

Journal:

Clinical Pharmacokinetics

Year:

2009

Language:

english

File:

PDF, 248 KB

english, 2009

2

Assessment of Pharmacokinetic Drug–Drug Interactions in Humans: In Vivo Probe Substrates for Drug Metabolism and Drug Transport Revisited

Fuhr, Uwe, Hsin, Chih-hsuan, Li, Xia, Jabrane, Wafaâ, Sörgel, Fritz

Journal:

Annual Review of Pharmacology

Year:

2019

Language:

english

File:

PDF, 1.21 MB

english, 2019

3

Medikamenteninteraktionen mit Chinolonen: Vorsicht bei Methylxanthinen, Antacida oder Warfarin!

Alexander Jetter, Uwe Fuhr

Journal:

Pharmazie in unserer Zeit

Year:

2001

Language:

german

File:

PDF, 327 KB

german, 2001

4

The fate of naringin in humans: A key to grapefruit juice-drug interactions?

Fuhr, Uwe, Kummert, Anja L.

Journal:

Clinical Pharmacology & Therapeutics

Year:

1995

Language:

english

File:

PDF, 928 KB

english, 1995

5

“Klinisch bedeutsame” neue Arzneimittelinteraktionen

Journal:

Medizinische Klinik - Intensivmedizin und Notfallmedizin

Year:

1999

File:

PDF, 756 KB

1999

6

Effects of grapefruit juice and smoking on verapamil concentrations in steady state

Uwe Fuhr, Herbert Müller-Peltzer, Rainer Kern, Pablo Lopez-Rojas, Manfred Jünemann, Sebastian Harder, Horst A. Staib

Journal:

European Journal of Clinical Pharmacology

Year:

2002

Language:

english

File:

PDF, 146 KB

english, 2002

7

Phenotyping ofN-acetyltransferase type 2 by caffeine from uncontrolled dietary exposure

Alexander Jetter, Martina Kinzig-Schippers, Michael Illauer, Robert Hermann, Katharina Erb, Jürgen Borlak, Helga Wolf, Gillian Smith, Ingolf Cascorbi, Fritz Sörgel, Uwe Fuhr

Journal:

European Journal of Clinical Pharmacology

Year:

2004

Language:

english

File:

PDF, 342 KB

english, 2004

8

Mesalazine pharmacokinetics and NAT2 phenotype

Hendrik Lück, Martina Kinzig, Alexander Jetter, Uwe Fuhr, Fritz Sörgel

Journal:

European Journal of Clinical Pharmacology

Year:

2009

Language:

english

File:

PDF, 179 KB

english, 2009

9

Relative potency of proton-pump inhibitors—comparison of effects on intragastric pH

Julia Kirchheiner, Silke Glatt, Uwe Fuhr, Ulrich Klotz, Ingolf Meineke, Thomas Seufferlein, Jürgen Brockmöller

Journal:

European Journal of Clinical Pharmacology

Year:

2009

Language:

english

File:

PDF, 302 KB

english, 2009

10

Opinion: Pharmacogenetics-based therapeutic recommendations — ready for clinical practice?

Kirchheiner, Julia, Fuhr, Uwe, Brockmöller, Jürgen

Journal:

Nature Reviews Drug Discovery

Year:

2005

Language:

english

File:

PDF, 491 KB

english, 2005

11

Drug Interactions with Grapefruit Juice

Professor Dr med Uwe Fuhr

Journal:

Year:

1998

Language:

english

File:

PDF, 188 KB

english, 1998

12

A HILIC-MS/MS assay for the quantification of metformin and sitagliptin in human plasma and urine: A tool for studying drug transporter perturbation

Scherf-Clavel, Oliver, Kinzig, Martina, Stoffel, Marc S., Fuhr, Uwe, Sörgel, Fritz

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Year:

2019

Language:

english

File:

PDF, 1010 KB

english, 2019

13

Frequency and Types of Pathological Upper Gastrointestinal Endoscopy Findings in Clinically Healthy Individuals

Scheidl, Elisabeth, Benz, Claus, Loeff, Peter, Groneck, Volker, KÃ¶nig, Andreas, Schulte-Fischedick, Alban, LÃ¼ck, Hendrik, Fuhr, Uwe

Journal:

Year:

2020

File:

PDF, 1.16 MB

2020

14

Reactivities of Organic Phase Biosensors 3: Electrochemical Study of Cytochrome P450cam Immobilized in a Methyltriethoxysilane Sol-Gel

Emmanuel I. Iwuoha, Stephen Kane, Conchita Ovin Ania, Malcolm R. Smyth, Paul R. Ortiz de Montellano, Uwe Fuhr

Journal:

Electroanalysis

Year:

2000

Language:

english

File:

PDF, 340 KB

english, 2000

15

ChemInform Abstract: Interactions of Medicaments with Quinolones

Alexander Jetter, Uwe Fuhr

Journal:

Year:

2001

File:

PDF, 23 KB

2001

16

Biotransformation of methylxanthines in mammalian cell lines genetically engineered for expression of single cytochrome P450 isoforms. Allocation of metabolic pathways to isoforms and inhibitory effects of quinolones

Uwe Fuhr, Johannes Doehmer, Narayana Battula, Catherine Wölfel, Ingrid Flick, Christine Kudla, Yango Keita, A.Horst Staib

Journal:

Year:

1993

Language:

english

File:

PDF, 1.24 MB

english, 1993

17

Design of asynchronous dielectric micromotors

Rolf Hagedorn, Günter Fuhr, Torsten Müller, Thomas Schnelle, Uwe Schnakenberg, Bernd Wagner

Journal:

Journal of Electrostatics

Year:

1994

Language:

english

File:

PDF, 1.99 MB

english, 1994

18

Determination of free and total 7-hydroxycoumarin in urine and serum by capillary electrophoresis

Declan P. Bogan, Brian Deasy, Richard O'Kennedy, Malcolm R. Smyth, Uwe Fuhr

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

1995

Language:

english

File:

PDF, 486 KB

english, 1995

19

Drug metabolism biosensors: electrochemical reactivities of cytochrome P450cam immobilised in synthetic vesicular systems

Emmanuel I Iwuoha, Shiba Joseph, Z Zhang, Malcolm R Smyth, Uwe Fuhr, Paul R Ortiz de Montellano

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Year:

1998

Language:

english

File:

PDF, 173 KB

english, 1998

20

Cytochrome P-450 Enzymes Contributing to Demethylation of Maprotiline in Man

Lars Brachtendorf, Alexander Jetter, K. Tobias Beckurts, Arnulf H. Hölscher, Uwe Fuhr

Journal:

Basic & Clinical Pharmacology & Toxicology

Year:

2002

Language:

english

File:

PDF, 101 KB

english, 2002

21

Affinities of Dihydrocodeine and its Metabolites to Opioid Receptors

Helmut Schmidt, Stefan V. Vormfelde, Klaus Klinder, Ursula Gundert-Remy, Christoph H. Gleiter, Gisela Skopp, Rolf Aderjan, Uwe Fuhr

Journal:

Basic & Clinical Pharmacology & Toxicology

Year:

2002

Language:

english

File:

PDF, 114 KB

english, 2002

22

Quantification of cyclophosphamide and its metabolites in urine using liquid chromatography/tandem mass spectrometry

Dirk Kasel, Alexander Jetter, Steffi Harlfinger, Wilhelm Gebhardt, Uwe Fuhr

Journal:

Rapid Communications in Mass Spectrometry

Year:

2004

Language:

english

File:

PDF, 325 KB

english, 2004

23

Quantification of mephenytoin and its metabolites 4′-hydroxymephenytoin and nirvanol in human urine using a simple sample processing method

Tobias Klaassen, Dirk Kasel, Stefanie Harlfinger, Uwe Fuhr

Journal:

Rapid Communications in Mass Spectrometry

Year:

2004

Language:

english

File:

PDF, 175 KB

english, 2004

24

Professor Norbert H. Rietbrock

Uwe Fuhr, Sebastian Harder, Brigitte Keller-Stanislawski, Petra Thürmann, Verbund Klinische Pharmakologie in Deutschland

Journal:

European Journal of Clinical Pharmacology

Year:

2003

Language:

english

File:

PDF, 111 KB

english, 2003

25

What is the true risk of a pharmacokinetic drug–drug interaction?

Journal:

European Journal of Clinical Pharmacology

Year:

2007

Language:

english

File:

PDF, 76 KB

english, 2007

26

Assessment of urinary mephenytoin metrics to phenotype for CYP2C19 and CYP2B6 activity

Tobias Klaassen, Alexander Jetter, Dorota Tomalik-Scharte, Dirk Kasel, Julia Kirchheiner, Ulrich Jaehde, Uwe Fuhr

Journal:

European Journal of Clinical Pharmacology

Year:

2008

Language:

english

File:

PDF, 236 KB

english, 2008

27

Modelling ocular pharmacokinetics of fluorescein administered as lyophilisate or conventional eye drops

Khaled Abduljalil, Michael Diestelhorst, Oxana Doroshyenko, Anja Lux, Andre Steinfeld, Sven Dinslage, Richard Süverkrüp, Uwe Fuhr

Journal:

European Journal of Clinical Pharmacology

Year:

2008

Language:

english

File:

PDF, 523 KB

english, 2008

28

Improvement in the handling of drug–drug interactions

Journal:

European Journal of Clinical Pharmacology

Year:

2008

Language:

english

File:

PDF, 130 KB

english, 2008

29

Professor Dr. Nina Bakracheva

Petra A. Thürmann, Emil Gatchev, Uwe Fuhr, Sebastian Harder

Journal:

European Journal of Clinical Pharmacology

Year:

2008

Language:

english

File:

PDF, 46 KB

english, 2008

30

Identification of a novel non-functionalCYP2D6allele,CYP2D6*69, in a Caucasian poor metabolizer individual

Andrea Gaedigk, Dorothee Frank, Uwe Fuhr

Journal:

European Journal of Clinical Pharmacology

Year:

2009

Language:

english

File:

PDF, 107 KB

english, 2009

31

Influence of posture on pharmacokinetics

Christian Queckenberg, Uwe Fuhr

Journal:

European Journal of Clinical Pharmacology

Year:

2009

Language:

english

File:

PDF, 187 KB

english, 2009

32

Phenotyping ofN-acetyltransferase type 2 and xanthine oxidase with caffeine: when should urine samples be collected?

Alexander Jetter, Martina Kinzig, Michael Rodamer, Dorota Tomalik-Scharte, Fritz Sörgel, Uwe Fuhr

Journal:

European Journal of Clinical Pharmacology

Year:

2009

Language:

english

File:

PDF, 172 KB

english, 2009

33

Torsades de pointes tachycardia induced by common cold compound medication containing chlorpheniramine

Amir M. Nia, Uwe Fuhr, Natig Gassanov, Erland Erdmann, Fikret Er

Journal:

European Journal of Clinical Pharmacology

Year:

2010

Language:

english

File:

PDF, 302 KB

english, 2010

34

Arginine vasopressin (AVP) and treatment with arginine vasopressin receptor antagonists (vaptans) in congestive heart failure, liver cirrhosis and syndrome of inappropriate antidiuretic hormone secretion (SIADH)

Natig Gassanov, Nasser Semmo, Mariam Semmo, Amir M. Nia, Uwe Fuhr, Fikret Er

Journal:

European Journal of Clinical Pharmacology

Year:

2011

Language:

english

File:

PDF, 359 KB

english, 2011

35

Clinical impact of fluvoxamine-mediated long QTU syndrome

Amir M. Nia, Kristina M. Dahlem, Natig Gassanov, Hansjörg Hungerbühler, Uwe Fuhr, Fikret Er

Journal:

European Journal of Clinical Pharmacology

Year:

2012

Language:

english

File:

PDF, 107 KB

english, 2012

36

Natriuretic peptides in therapy for decompensated heart failure

Natig Gassanov, Esther Biesenbach, Evren Caglayan, Amir Nia, Uwe Fuhr, Fikret Er

Journal:

European Journal of Clinical Pharmacology

Year:

2012

Language:

english

File:

PDF, 475 KB

english, 2012

37

Study of coumarin metabolism by human liver microsomes using capillary electrophoresis

Brian Deasy, Declan P. Bogan, Malcolm R. Smyth, Richard O'Kennedy, Uwe Fuhr

Journal:

Analytica Chimica Acta

Year:

1995

Language:

english

File:

PDF, 564 KB

english, 1995

38

Inhibitory Effects of Silibinin on Cytochrome P-450 Enzymes in Human Liver Microsomes

Svane Beckmann-Knopp, Stephan Rietbrock, Roland Weyhenmeyer, Ronald H. Böcker, K. Tobias Beckurts, Werner Lang, Miriam Hunz, Uwe Fuhr

Journal:

Basic & Clinical Pharmacology & Toxicology

Year:

2000

Language:

english

File:

PDF, 111 KB

english, 2000

39

Inhibitory Effects of Trospium Chloride on Cytochrome P450 Enzymes in Human Liver Microsomes

Svane Beckmann-Knopp, Stephan Rietbrock, Roland Weyhenmeyer, Ronald H. Böcker, K. Tobias Beckurts, Werner Lang, Uwe Fuhr

Journal:

Basic & Clinical Pharmacology & Toxicology

Year:

1999

Language:

english

File:

PDF, 570 KB

english, 1999

40

Assessment of CYP1A2 Activity in Clinical Practice: Why, How, and When?

Mirko S. Faber, Alexander Jetter, Uwe Fuhr

Journal:

Basic & Clinical Pharmacology & Toxicology

Year:

2005

Language:

english

File:

PDF, 109 KB

english, 2005

41

The Role of Human CYP2C8 and CYP2C9 Variants in Pioglitazone Metabolism In Vitro

Eugen Muschler, Jawahar Lal, Alexander Jetter, Anke Rattay, Ulrich Zanger, Gregor Zadoyan, Uwe Fuhr, Julia Kirchheiner

Journal:

Basic & Clinical Pharmacology & Toxicology

Year:

2009

Language:

english

File:

PDF, 207 KB

english, 2009

42

Theophylline metabolism affected by mexiletine

Rost, Karl Ludwig, Fuhr, Uwe, Roots, Ivar, Staib, A Horst

Journal:

Clinical Pharmacology & Therapeutics

Year:

1992

Language:

english

File:

PDF, 357 KB

english, 1992

43

Pharmacokinetics, Pharmacodynamics, and Comparative Bioavailability of Single, Oral 2-mg Doses of Dexamethasone Liquid and Tablet Formulations: A Randomized, Controlled, Crossover Study in Healthy Adult Volunteers

Christian Queckenberg, Bertil Wachall, Valerie Erlinghagen, Paola Di Gion, Dorota Tomalik-Scharte, Mona Tawab, Kathleen Gerbeth, Uwe Fuhr

Journal:

Clinical Therapeutics

Year:

2011

Language:

english

File:

PDF, 433 KB

english, 2011

44

Differences in caffeine and paraxanthine metabolism between human and murine CYP1A2

Andreas Labedzki, Jeroen Buters, Wafaâ Jabrane, Uwe Fuhr

Journal:

Biochemical Pharmacology

Year:

2002

Language:

english

File:

PDF, 233 KB

english, 2002

45

An amperometric biosensor with human CYP3A4 as a novel drug screening tool

Shiba Joseph, James F. Rusling, Yuri M. Lvov, Thomas Friedberg, Uwe Fuhr

Journal:

Biochemical Pharmacology

Year:

2003

Language:

english

File:

PDF, 191 KB

english, 2003

46

Ciprofloxacin-caffeine: A drug interaction established using in vivo and in vitro investigations

Sebastian Harder, Uwe Fuhr, A. Horst Staib, Thomas Wolff

Journal:

The American Journal of Medicine

Year:

1989

Language:

english

File:

PDF, 378 KB

english, 1989

47

Absorption differences of ciprofloxacin along the human gastrointestinal tract determined using a remote-control drug delivery device (HF-capsule)

A. Horst Staib, Dieter Beermann, Sebastian Harder, Uwe Fuhr, Dieter Liermann

Journal:

The American Journal of Medicine

Year:

1989

Language:

english

File:

PDF, 410 KB

english, 1989

48

Biotransformation of caffeine and theophylline in mammalian cell lines genetically engineered for expression of single cytochrome P450 isoforms

Uwe fuhr, Johannes Doehmer, Narayana Battula, Catherine Wölfel, Christine Kudla, Yango Keita, A.Horst Staib

Journal:

Biochemical Pharmacology

Year:

1992

Language:

english

File:

PDF, 1.03 MB

english, 1992

49

Characterization of non-extractable residues of the fungicide dithianon in soil using 13C/14C-labelling techniques

Uwe Wanner, Fritz Führ, Albert A. deGraaf, Peter Burauel

Journal:

Environmental Pollution

Year:

2005

Language:

english

File:

PDF, 443 KB

english, 2005

50

Influence of the amendment of corn straw on the degradation behaviour of the fungicide dithianon in soil

Uwe Wanner, Fritz Führ, Peter Burauel

Journal:

Environmental Pollution

Year:

2005

Language:

english

File:

PDF, 451 KB

english, 2005